10 Top Digital Twin Startups in 2025

Imagine a world where every physical object—from industrial machines to human organs—has a virtual twin that reflects its real-time state. This is the power of digital twin technology.

The global market is expected to soar from USD 24.48 billion in 2025 to USD 259.32 billion by 2032, with a CAGR of 40.1% during the period.

So, how does the technology work? A digital twin is a transformative innovation that provides real-time simulations and predictive insights into a digital asset or product to understand its complications.

The technique emerged in 2002 when Dr. Michael Grieves explained the idea of creating a digital model of a physical product and using it for analysis. However, some research papers say the technology has been used since the 1960s.

More than 910 startups are eager to use this technology and have employed 360,000 people.

The developments in IoT, AI, and data analytics are the key drivers behind this immense growth. Let's look at some of the digital twin startups leading in 2025.

1. Toobler: Intelligent & Sustainable Asset Management

Founded: 2008 | Location: Kochi, India

Toobler is one of the digital twin companies in India offering customized solutions. The company mainly focuses on smart infrastructure and integrates IoT, cloud, and data analytics for real-time upgrades.

Standout Features:

The foundation for Toobler's digital twin solutions is an IoT-enabled platform that enables smooth real-time data integration. This allows companies to make more informed and efficient data-driven decisions.

Their solutions allow businesses to replicate, track, and improve performance in real-time by creating virtual representations of physical assets.

Sustainability is a top priority for Toobler, which uses digital twins to improve environmental and energy management.

Because of their open-source methodology and agile development process, their solutions can be tailored to meet various needs. This guarantees flexibility in implementation and service costs.

The organization is a trusted partner in several industries because of its dedication to sustainability and innovation.

Target Industries:

• Manufacturing: Toobler monitors equipment and procedures through digital twins in manufacturing to increase output and decrease downtime. This assists industrial organizations in streamlining their operations.

• Energy & Utilities: Digital twins in the energy and utilities industry help with predictive maintenance, real-time energy usage monitoring, and guaranteeing operational effectiveness.

• Smart Cities: Toobler's digital twin in smart cities is essential to creating smart cities because it improves infrastructure planning, resource optimization, and traffic control.

• Construction: Toobler employs digital twins in the construction sector to improve asset lifecycle management, resource scheduling, and project planning.

• Automotive: Digital twins in automotive can replicate the performance, spot problems early, and increase design accuracy by building virtual models of cars, which will ultimately improve vehicle quality, safety, and efficiency.

• Healthcare: Through real-time asset and medical device monitoring, Toobler's digital twins in healthcare enhance patient care. Through continuous monitoring, their solutions improve patient safety and care outcomes, guarantee equipment reliability, and enable predictive maintenance.

• Supply Chain Management: Toobler employs digital twins in supply chain management to streamline delivery systems, track inventories, and keep an eye on logistics. Real-time data from their products help firms minimize inefficiencies, enhance resource management, and simplify operations.

2. YouNeed3D: Asset & Infrastructure Insights

Founded: 2020 | Location: Switzerland

This digital twin startup specializes in designing complex 3D models for industrial facilities and construction sites. The platform allows clients to access the environments virtually and understand critical data without physically visiting the site.

Standout Features:

The platform integrates IoT sensors and modern analytics, which are mainly used by construction and facility management companies. It creates interactive models mimicking real-world spaces. Monitoring assets in these spaces ensures better collaboration at lower operational costs.

Target Industries:

• Construction

• Architecture

• Industrial Engineering

• Facility Management

3. Twinsity: High-Performance Infrastructure Analysis

Founded: 2019 | Location: Kassel, Germany

The top digital twin startup provides users with a high-performance platform called TWINSPECT for analyzing large and complex infrastructure. The interactive 3D models are combined with drone imagery for a practical inspection.

Standout Features:

Its key features include AI-assisted damage detection, real-time collaboration, and GDPR-compliant cloud hosting via AWS. These security features allow clients to quickly examine their assets with better communication and decision management.

Target Industries:

• Infrastructure

• Construction

• Industrial Facilities

• Energy & Utilities

4. Enreport: Energy Consumption Forecasting

Founded: 2022 | Location: Espoo, Finland

This innovative digital twin startup leverages predictive analytics to improve energy demand and supply. These modern solutions provide energy efficiency and environmental sustainability. With real-time 3D models, companies can easily navigate, monitor, and simulate energy consumption.

Standout Features:

Through its precise energy forecasting model, IoT, and AI integrations, companies can easily fulfill their sustainable and compliance goals. Moreover, the actionable insights merged with 3D models help companies reduce energy waste and carbon footprint in real-time.

Target Industries:

• Manufacturing

• Energy & Utilities

• Green Building

• Facility Management

5. Carbontribe: CO2 Emission Reduction Data

Founded: 2023 | Location: Estonia

With its explicit simulations and real-time insights, the AI-driven digital twin startup aims to reduce carbon emissions for its client companies. The platform creates virtual replicas of industrial processes that help companies identify and develop strategies that consider emissions.

Standout Features:

The platform utilizes AI and Web3 technologies to help remove Greenhouse gases with its carbon credit solutions. Additionally, it issues ESG (environmental, social, and governance) certification to companies that use its platform to offset industrial carbon emissions.

Target Industries:

• Manufacturing

• Forestry & Land Use

• Agriculture

• Technology

6. OneTwenty: Glycemic Control Technology Model

Founded: 2022 | Location: Zurich

It is rare to find a digital twin startup focusing on the healthcare sector. OneTwenty's bioX® DT platform caters to clients or companies seeking glycemic control. The company has three applications: bioX neoAP, a closed-loop automatic insulin delivery (LCL-AID) system; bioX DT, a digital twin engine; and bioX sensAI, a sensor optimization solution that translates raw sensor data into optimal bio-proofs.

Standout Features:

With its digital twin feature, the platform helps medical researchers and organizations predict blood sugar fluctuations with diabetes management. The technology provides individuals with insights that reduce the need for trial-and-error in actual patients. This further improves the research models and lowers the costs for future treatments.

Target Industries:

• Digital Health

• Medical & Healthcare

• Technology

• Medical Research

7. NEWTWEN: Next-Gen Digital Twins for Automotive Systems

Founded: 2020 | Location: Padua, Italy

The platform offers digital twin solutions for real-time control and predictive maintenance of electromechanical and electronic components in electric powertrains. It further uses proprietary algorithms to create accurate digital twins with embedded chips, helping evaluate factors such as temperature and torque.

Standout Features:

The efficient digital twin models help industries obtain optimal thermal management with predictive maintenance and improvement for electric powertrain systems. Furthermore, the platform allows automotive companies to upgrade their hardware systems at lower maintenance costs.

Target Industries:

• Automotive

• Renewable Energy

• Power Electronics

• Industrial Automation

8. ETELIER: Virtual Fitting Trials

Founded: 2021 | Location: United States

Imagine a startup offering fitting trials right onto your couch before you make a purchase. ETELIER does that for you.

This digital twin startup provides remote 3D body scanning and converts simple videos into detailed, lifelike 3D body models. The company aims to make online shopping more fun and AI-oriented.

Standout Features:

Fashion brands and retailers can take advantage of it. Using the services, they can quickly help customers try on clothes virtually using augmented reality (AR). The users can see how products honestly fit their actual body shape with no messy tape measures or assumptions.

Besides measurements, the platform also scans the color profiles and suggests clothing based on the data.

Target Industries:

• Fashion

• E-commerce

• Apparel Manufacturing

• Retail

9. AIBODY: Human Digital Twin in Healthcare

Founded: 2020 | Location: London, UK

AIBODY leverages real-time, physiology-based digital twin technology to create 3D models that mimic the insides of a human body. The model is built using the subcellular level and replication of the standard and abnormal physiology, treatment options, and their results on patients.

Standout Features:

The platform's digital physiology studies 132,000+ parameters, providing users with an advanced simulated model. This type of digital twin as a service benefits healthcare and pharmaceutical companies.

They can easily monitor and simulate future conditions and test them with treatments without harming real humans. The companies can integrate this service into their websites and AR portals to enhance their medical training and clinical support.

Target Industries:

• Healthcare

• Research Organizations

• Virtual Medicine

• Medical Education

10. Blynksolve: Complicated Drug Substance Manufacturing

Founded: 2022 | Location: Dublin, Ireland

Companies using digital twin technology like Blynksolve were founded to provide simulated solutions to pharmaceutical manufacturers. Their real-time models aim to simplify drug substance production by providing step-by-step process visualization and effective quality control.

Standout Features:

The company offers digital twin solutions fragmented into—Blynkinsights and blynkdesign. The platform provides easy tech transfer, MES design, CDMO collaboration, and quality risk assessments like HAZOP and FMEA.

With its plug-and-play integrations, Blynksolve makes the complex DS process mapping easy for pharma companies. Additionally, the AI-powered system backed by the data reduces time-outs and energy costs.

Target Industries:

• Pharmaceutical Manufacturing

• Biotech

• Automotive

• Industrial IoT

Digital twins are not just a mere trend but an effective simulation strategy for solving complex industry challenges.

With the emergence of startup culture and AI-driven operations, digital twin companies replicate, track, and predict real-world behavior using virtual models.

The vast usage of IoT devices, expected to reach 30.9 billion by 2025, will power digital twins. Let's look at some of the key factors driving the technology revolution.

• Digital transformation and IoT

• Modern advancements in AI, cloud, and data analytics

• Compliance and societal pressure to attain sustainability

• Immediate need for low-cost and higher-efficiency models

• Utilizing predictive analytics to minimize the risks

These top digital twin startups in USA are not only gaining from technology but have also redefined industrial operations. They cater to the manufacturing, smart cities, retail e-commerce, automotive, pharmaceutical, and healthcare industries.

Businesses and investors must keep a keen eye on the top digital twin companies to stay ahead of the competition. As the global digital twin market skyrockets, platforms investing in this modern innovation will lead the space.

Are you curious about how digital twins connect the virtual and physical worlds? Talk to a Toobler expert and experience the real-time simulation for your business

1. Do I require any unique hardware or sensors to apply them?

No. Many upcoming startups like Toobler provide plug-and-play integrations with IoT adoption, making it cost-effective and flexible.

2. Can small businesses also adopt the digital twin solutions?

Definitely!Utilizing these startups' solutions will help you scale and give you a futuristic view of the industry. It is better to subscribe to these services before it's too late.

3. Are these platforms developer-friendly with SDKs and documentation?

Yes. Digital twin startups like Toobler provide developer toolkits, REST APIs, and elaborate documentation. This allows companies to customize their solutions easily and developers to integrate them easily.

4. How do these digital twin startups combine with the existing IT frameworks?

Almost every startup working with this technology offers API-first platforms, cloud-native architectures, and flexible solutions. Hence, these integrations easily merge with ERP, MES, and IoT platforms.

5. What challenges might IT teams face while using these systems, and how do startups help them?

Some challenges include legacy systems, ensuring data compatibility, and scalability. However, startups with digital twin solutions solve these issues through cost-effective integrations, open standards (like OPC UA and JSON), and placing cloud-native structures.